.encyclopedia-overview{border-collapse:collapse;table-layout:fixed;color:#30473d;overflow-wrap:anywhere;width:100%;max-width:100%;margin:20px 0 0;font-size:15px;line-height:1.8}.encyclopedia-overview caption{color:#244638;text-align:left;padding:0 0 10px;font-size:14px;font-weight:700}.encyclopedia-overview :is(th,td){text-align:left;vertical-align:top;border:1px solid #d8e2dc;padding:12px 16px}.encyclopedia-overview th{background:#edf3ef;width:140px;font-weight:650}.encyclopedia-overview td{background:#fff}.encyclopedia-overview a{color:#176749;text-underline-offset:3px}.encyclopedia-overview-links{flex-wrap:wrap;gap:6px 16px;display:flex}.encyclopedia-contents{color:#30473d;background:#f7faf7;border:1px solid #d8e2dc;width:min(100% - 40px,1020px);margin:24px auto 0;padding:18px 20px;font-size:14px;line-height:1.6}.encyclopedia-contents h2{margin:0 0 10px;font-size:17px;line-height:1.5}.encyclopedia-contents ol{margin:0;padding:0;list-style:none}.encyclopedia-contents>ol{columns:2;column-gap:36px}.encyclopedia-contents li{break-inside:avoid;margin:0;padding:0}.encyclopedia-contents li ol{padding-left:16px}.encyclopedia-contents a{color:#176749;overflow-wrap:anywhere;align-items:baseline;gap:8px;min-height:36px;padding:6px 0;text-decoration:none;display:flex}.encyclopedia-contents a:hover{text-underline-offset:3px;text-decoration:underline}.encyclopedia-contents-number{font-variant-numeric:tabular-nums;color:#687d70;flex-shrink:0}:is(.encyclopedia-contents a:focus-visible,.encyclopedia-overview a:focus-visible){outline-offset:4px;outline:2px solid #217354}.encyclopedia-reading-sections{gap:24px;min-width:0;display:grid}.encyclopedia-document [id]{scroll-margin-top:104px}@media (max-width:600px){.encyclopedia-overview{font-size:14px}.encyclopedia-overview :is(th,td){padding:10px}.encyclopedia-overview th{width:90px}.encyclopedia-contents{padding:16px}.encyclopedia-contents>ol{columns:1}.encyclopedia-contents a{min-height:44px;padding:10px 0}}#main-content .reference-wiki-page{--reference-ink:#143d32;--reference-accent:#176a50;--reference-text:#344b42;--reference-muted:#62736c;--reference-line:#d4dfd8;--reference-wash:#f3f7f4;min-height:100vh;color:var(--reference-text);background:#f2f5f3}#main-content .reference-wiki-document{counter-reset:reference-section 1;border-inline:1px solid var(--reference-line);background:#fff;width:min(100%,1120px);margin:0 auto;padding:34px 48px 76px;box-shadow:0 16px 44px #143d320f}#main-content .reference-wiki-hero{border-bottom:1px solid var(--reference-line);grid-template-columns:minmax(0,1fr) 250px;align-items:start;gap:38px;padding:10px 0 30px;display:grid}#main-content .reference-wiki-hero-copy{min-width:0}#main-content .reference-wiki-eyebrow{color:var(--reference-accent);letter-spacing:.08em;margin:0 0 10px;font-size:13px;font-weight:800}#main-content .reference-wiki-hero h1{color:var(--reference-ink);letter-spacing:-.05em;margin:0;font-size:clamp(38px,5vw,54px);font-weight:850;line-height:1.16}#main-content .reference-wiki-subtitle{color:#176a50;letter-spacing:-.025em;margin:13px 0 0;font-size:clamp(18px,2.2vw,22px);font-weight:780;line-height:1.5}#main-content .reference-wiki-alias{color:var(--reference-muted);margin:8px 0 0;font-size:13px;font-weight:650}#main-content :is(.reference-wiki-description,.reference-wiki-summary){max-width:720px;color:var(--reference-text);font-size:16px;line-height:1.88}#main-content .reference-wiki-description{margin:18px 0 0}#main-content .reference-wiki-summary{color:#52675d;margin:8px 0 0}#main-content .reference-wiki-meta{color:#60736a;flex-wrap:wrap;gap:6px 14px;margin-top:18px;font-size:12px;font-weight:700;display:flex}#main-content .reference-wiki-meta span+span:before{content:"·";color:#9aa9a1;margin-right:14px}#main-content .reference-wiki-document .editorial-page-image--aside figcaption{clip:rect(0, 0, 0, 0);white-space:nowrap;border:0;width:1px;height:1px;margin:-1px;padding:0;position:absolute;overflow:hidden}#main-content .reference-wiki-index{grid-template-columns:minmax(230px,292px) minmax(0,1fr);align-items:start;gap:28px;margin:30px 0 8px;display:grid}body.knowledge-theme.interaction-theme #main-content .reference-wiki-index .encyclopedia-contents{top:calc(var(--site-header-height,110px) + 14px);border:1px solid var(--reference-line);border-left:3px solid var(--reference-accent);background:#fbfcfb;border-radius:5px;width:100%;margin:0;padding:18px;position:sticky}#main-content .reference-wiki-index .encyclopedia-contents>ol{columns:1}#main-content .reference-wiki-index .encyclopedia-contents a{border-bottom:1px solid #e5ece7;min-height:38px;padding:6px 4px;font-size:13.5px}#main-content .reference-wiki-index .encyclopedia-contents li:last-child>a{border-bottom:0}#main-content .reference-wiki-overview{min-width:0;margin:0;padding:0}#main-content .reference-wiki-overview>h2,#main-content .reference-wiki-document [data-reference-section]>h2,#main-content .reference-wiki-document [data-reference-section]>div:first-child>h2,#main-content .reference-wiki-document [data-reference-section]>div:first-child>div>h2{color:var(--reference-ink);letter-spacing:-.035em;border-bottom:1px solid #abc2b5;margin:0 0 16px;padding:0 0 12px;font-size:clamp(22px,2.7vw,28px);font-weight:800;line-height:1.45}#main-content .reference-wiki-overview>h2:before{content:"1. ";color:var(--reference-accent)}#main-content .reference-wiki-document [data-reference-section]{counter-increment:reference-section}#main-content .reference-wiki-document [data-reference-section]>h2:before,#main-content .reference-wiki-document [data-reference-section]>div:first-child>h2:before,#main-content .reference-wiki-document [data-reference-section]>div:first-child>div>h2:before{content:counter(reference-section) ". ";color:var(--reference-accent);font-variant-numeric:tabular-nums}#main-content .reference-wiki-body .article-card{box-shadow:none;background:0 0;border:0;border-radius:0;margin-top:42px;padding:0}#main-content .reference-wiki-topic-body{width:min(100%,780px);margin:0 auto;padding:12px 0 0;display:block}#main-content .reference-wiki-topic-body .subject-pathways{margin-top:34px}#main-content .reference-wiki-topic-body [data-link-group=same-disease] a{box-shadow:none;background:#fff;border-radius:4px}#main-content .reference-wiki-body>div>.article-card:first-child{margin-top:0}#main-content .reference-wiki-body .article-card :is(p,li){font-size:15.5px;line-height:1.9}#main-content .reference-wiki-body .article-card :is(.rounded-xl,.rounded-2xl){border-radius:5px}#main-content .reference-wiki-body aside .article-card{border:1px solid var(--reference-line);background:#fbfcfb;border-radius:5px;margin:0;padding:20px;position:sticky;top:92px}#main-content .reference-wiki-body aside .article-card h2{border:0;padding:0}#main-content .reference-wiki-alert{border-radius:5px;margin-top:42px}#main-content .reference-wiki-body>.reference-wiki-alert:first-child{margin-top:6px}#main-content .reference-wiki-document>section[id]{border-top:1px solid var(--reference-line);background:0 0}#main-content .reference-wiki-document>section[id]>div{padding-block:38px}#main-content .reference-wiki-document>section[id] h2{color:var(--reference-ink);letter-spacing:-.03em;font-size:23px}#main-content .reference-wiki-document>section[id] a[class*=rounded-2xl]{box-shadow:none;border-radius:5px}#main-content .reference-wiki-document [id]{scroll-margin-top:calc(var(--site-header-height,110px) + 18px)!important}#main-content .symptom-index-body{max-width:1060px;display:block}#main-content .symptom-index-safety{align-items:flex-start;gap:14px;margin:0 0 34px;padding:18px 20px;display:flex}#main-content .symptom-index-safety>svg{color:#ad4b27;flex:none;width:24px;height:24px}#main-content .symptom-index-safety strong{color:#6b341f;margin-bottom:4px;display:block}#main-content .symptom-index-safety p{color:#674639;margin:0}#main-content .symptom-index-group{border-top:1px solid #cbd9d2;padding:0 0 36px;scroll-margin-top:24px}#main-content .symptom-index-group-heading{padding:24px 0 16px}#main-content .symptom-index-group-heading h2{margin:0 0 8px}#main-content .symptom-index-group-heading p{color:#526860;margin:0}#main-content .symptom-index-group ul{border-top:1px solid #dbe4df;grid-template-columns:repeat(2,minmax(0,1fr));gap:0 26px;margin:0;padding:0;list-style:none;display:grid}#main-content .symptom-index-group li{border-bottom:1px solid #dbe4df}#main-content .symptom-index-group a{color:#173f34;justify-content:space-between;align-items:center;gap:16px;min-height:78px;padding:13px 4px;text-decoration:none;display:flex}#main-content .symptom-index-group a:hover{color:#006c4e;background:#f7faf8}#main-content .symptom-index-group a>span{gap:4px;display:grid}#main-content .symptom-index-group a strong{font-size:1rem}#main-content .symptom-index-group a small{color:#61736c;font-size:.82rem;line-height:1.55}#main-content .symptom-index-group a>svg{flex:none;width:18px;height:18px}#main-content .symptom-index-next{border-top:1px solid #cbd9d2;padding:24px 0 0;scroll-margin-top:24px}#main-content .symptom-index-next>p{color:#526860;max-width:780px}#main-content .symptom-index-next nav{grid-template-columns:repeat(3,minmax(0,1fr));gap:10px;margin-top:18px;display:grid}#main-content .symptom-index-next a{color:#123d31;border:1px solid #0f5b46;border-radius:10px;grid-template-columns:auto 1fr auto;align-items:center;gap:12px;min-height:84px;padding:14px 16px;text-decoration:none;display:grid}#main-content .symptom-index-next a:hover{background:#eff7f3}#main-content .symptom-index-next a>svg{width:21px;height:21px}#main-content .symptom-index-next a span{gap:3px;display:grid}#main-content .symptom-index-next a small{color:#5d7169;font-size:.78rem;line-height:1.45}#main-content .disease-index-legal{border-top:1px solid #cbd9d2;margin-bottom:36px;padding:0 0 34px}#main-content .disease-index-legal .encyclopedia-overview th{width:30%;min-width:190px}#main-content .disease-grade-links{gap:7px;display:grid}#main-content .disease-grade-links>span:first-child{color:#435c52}#main-content .disease-grade-links>span:nth-child(2){line-height:1.75}#main-content .disease-grade-links a{color:#0b6a4d;text-underline-offset:3px;font-weight:750}#main-content .disease-grade-links small{color:#6c7b75;font-size:.76rem;font-weight:700}#main-content .disease-index-source{color:#62736c;text-align:right;margin:12px 0 0;font-size:.78rem}#main-content .disease-index-source a{color:#0b6a4d;font-weight:750}#main-content .disease-index-body>[data-page-entry-ad]{margin:0 0 38px}@media (max-width:1400px){body.knowledge-theme:has(#main-content .reference-wiki-page) .floating-share:not(.is-price-tool){width:calc(100% - 36px);max-width:680px;margin:20px auto 28px;display:block;position:static;inset:auto;transform:none}body.knowledge-theme:has(#main-content .reference-wiki-page) .floating-share:not(.is-price-tool) button{width:100%;min-width:0;height:auto;min-height:52px;box-shadow:none;background:#f3f7f3;border:1px solid #bfd1c5;border-radius:6px;gap:12px;padding:12px 16px;animation:none;display:flex;transform:none}body.knowledge-theme:has(#main-content .reference-wiki-page) .floating-share:not(.is-price-tool) :is(.floating-share-spark,.floating-share-ripple,.floating-share-progress,.floating-share-compact-label,.floating-share-link){display:none}body.knowledge-theme:has(#main-content .reference-wiki-page) .floating-share:not(.is-price-tool) button:before{display:none}body.knowledge-theme:has(#main-content .reference-wiki-page) .floating-share:not(.is-price-tool) button:after{display:none}body.knowledge-theme:has(#main-content .reference-wiki-page) .floating-share:not(.is-price-tool) .floating-share-copy{opacity:1;white-space:normal;display:block;position:static;transform:none}body.knowledge-theme:has(#main-content .reference-wiki-page) .floating-share:not(.is-price-tool) .floating-share-copy :is(small,em){display:none}body.knowledge-theme:has(#main-content .reference-wiki-page) .floating-share:not(.is-price-tool) .floating-share-mark{width:24px;min-width:24px;height:24px;box-shadow:none;background:0 0;border:0;border-radius:0;display:grid;overflow:visible}body.knowledge-theme:has(#main-content .reference-wiki-page) .floating-share:not(.is-price-tool) .floating-share-mark>img{display:none}body.knowledge-theme:has(#main-content .reference-wiki-page) .floating-share:not(.is-price-tool) .floating-share-mark>svg{width:24px;height:24px;color:var(--reference-accent);background:0 0;border:0;padding:0;position:static}}@media (max-width:820px){#main-content .reference-wiki-document{width:100%;box-shadow:none;border-inline:0;padding:26px 22px 60px}#main-content .reference-wiki-hero{grid-template-columns:1fr;gap:20px}#main-content .reference-wiki-hero .editorial-page-image--aside{width:min(100%,240px);margin:0 auto}#main-content .reference-wiki-index{grid-template-columns:1fr}body.knowledge-theme.interaction-theme #main-content .reference-wiki-index .encyclopedia-contents{position:static}#main-content .reference-wiki-body{grid-template-columns:1fr;padding-inline:0}#main-content .symptom-index-group ul,#main-content .symptom-index-next nav{grid-template-columns:1fr}}@media (max-width:600px){#main-content .reference-wiki-document{padding:20px 16px 48px}#main-content .reference-wiki-hero{grid-template-columns:1fr;gap:20px}#main-content .reference-wiki-hero .editorial-page-image--aside{width:min(100%,240px);margin:0 auto}#main-content .reference-wiki-hero h1{font-size:clamp(34px,11vw,44px)}#main-content .reference-wiki-subtitle{font-size:18px}#main-content .reference-wiki-description,#main-content .reference-wiki-summary{font-size:15px;line-height:1.8}#main-content .reference-wiki-meta{gap:4px 10px}#main-content .reference-wiki-meta span+span:before{margin-right:10px}#main-content .symptom-index-body{padding-inline:0}#main-content .symptom-index-safety{padding:15px}#main-content .symptom-index-group a{min-height:70px}#main-content .disease-index-legal .encyclopedia-overview th{width:38%;min-width:112px}#main-content .disease-index-source{text-align:left}#main-content .reference-wiki-document>section[id]>div{padding-inline:0}}@media (max-width:480px){.disease-reading-card{padding-inline:12px}.disease-reading-card .reading-comparison-table th,.disease-reading-card .reading-comparison-table td{padding:10px 8px}.disease-reading-card .reading-comparison-table th:first-child{width:36%;min-width:104px}#main-content .symptom-publication.reference-wiki-page #urgent ul{grid-template-columns:1fr}}